Author

Pravin Kumar R.

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Likith Muthuraj· 2 shared Nikhil U. NairiD· 2 shared Aaron M. LoveiD· 1 shared Abhishek KumariD· 1 shared Christine Nicole S. SantosiD· 1 shared Christopher G. Toomey· 1 shared Dhinesh Kumar Santhamoorthy· 1 shared Hannah L. Lynch· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBioengineering

Likith Muthuraj

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2 papers

Recent·Most cited

An engineered disulfide staple restricts lid loop dynamics and alters substrate specificity of phenylalanine ammonia-lyase

Rebecca Condruti, Likith Muthuraj, Jeevan K. Prakash, Samuel D. Littman, Pravin Kumar R., Nikhil U. Nair

The paper investigates the role of a dynamic loop in AvPAL by engineering disulfide bonds to restrict its mobility, revealing its regulatory function in substrate specificity.

bioRxiv · May 6, 2026 · PreprintBioengineering

A Novel Phosphatase Reverses the Leloir Pathway to Promote Tagatose Synthesis from Glucose

Aaron M. Love, Christopher G. Toomey, Abhishek Kumar, Sukesh Narayan Kashyap, Dhinesh Kumar Santhamoorthy, Likith Muthuraj, Hannah L. Lynch, Parayil Kumaran Ajikumar, Pravin Kumar R., Nikhil U. Nair, Christine Nicole S. Santos

This paper describes a novel biochemical pathway using a phosphatase to reverse the Leloir pathway in E. coli, enabling direct tagatose synthesis from glucose with high yield.

bioRxiv · Jul 29, 2025 · PreprintBioengineering