Author

Prema C. Iyer

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ari M. SelzeriD· 1 shared Carlos Jaime CamachoiD· 1 shared Gabriella GerlachiD· 1 shared Giancarlo Gonzalez-Areizaga· 1 shared John R. EngeniD· 1 shared Rieko IshimaiD· 1 shared Stephanie Y. Cui· 1 shared Thomas E. SmithgalliD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

Ari M. SelzerORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck

Ari M. Selzer, Gabriella Gerlach, Giancarlo Gonzalez-Areizaga, Thomas E. Wales, Stephanie Y. Cui, Prema C. Iyer, John R. Engen, Carlos Jaime Camacho, Rieko Ishima, Thomas E. Smithgall

This study identifies PDA1 as an SH3-binding allosteric modulator that stabilizes Hck conformation, potentially enhancing combination therapy with ATP-site inhibitors.

Journal of Biological Chemistry · Dec 13, 2024Peer-reviewedPharmacology & Toxicology