Author

Gabriella Gerlach

University of PittsburghORCID 0000-0003-2352-2963Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ari M. SelzeriD· 1 shared Carlos Jaime CamachoiD· 1 shared Giancarlo Gonzalez-Areizaga· 1 shared John R. EngeniD· 1 shared Prema C. Iyer· 1 shared Rieko IshimaiD· 1 shared Stephanie Y. Cui· 1 shared Thomas E. SmithgalliD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

Ari M. SelzerORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyJournal of Biological ChemistryPeer-reviewedDec 13, 2024

An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck

Ari M. Selzer, Gabriella Gerlach, Giancarlo Gonzalez-Areizaga…·Thomas E. Smithgall

This study identifies PDA1 as an SH3-binding allosteric modulator that stabilizes Hck conformation, potentially enhancing combination therapy with ATP-site inhibitors.

3 citations

humanproteomics

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