Ewing sarcoma breakpoint region 1 prevents transcription-associated genome instability
Nitish Mittal, Christophe Kunz, Foivos Gypas, Shivendra Kishore, Georges Martin, Friedel Wenzel, Erik van Nimwegen, Primo Schaer, Mihaela Zavolan
This study shows that EWSR1 prevents DNA double-strand breaks by binding to intronic regions in its own locus and maintaining genomic stability.
bioRxiv · Dec 15, 2015 · PreprintSystems Biology