Author

Georges Martin

University of Basel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Mihaela ZavolaniD· 4 shared Andreas J GruberiD· 2 shared Erik van NimwegeniD· 2 shared Ralf Schmidt· 2 shared Souvik GhoshiD· 2 shared Andreas R Gruber· 1 shared Arnau Vina-Villaseca· 1 shared Christophe Kunz· 1 shared

Activity by Year

2015-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersSystems Biology

Mihaela ZavolanORCID

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Author profile →

4 papers

Recent·Most cited

Discovery of physiological and cancer-related regulators of 3’ UTR processing with KAPAC

Andreas J Gruber, Ralf Schmidt, Souvik Ghosh, Georges Martin, Erik van Nimwegen, Mihaela Zavolan

The paper develops PAQR and KAPAC to analyze PAS use and motif activities in RNA-seq data, identifying Polypyrimidine tract binding protein 1 as a regulator of PAS choice in glioblastoma.

Genome biology · Mar 28, 2018Peer-reviewedSystems Biology

High-throughput identification of C/D box snoRNA targets with CLIP and RiboMeth-seq.

Rafal Gumienny, Dominik Jedlinski, Georges Martin, Arnau Vina-Villaseca, Mihaela Zavolan

The paper develops computational methods to identify C/D box snoRNA targets using CLIP and RiboMeth-seq data, revealing new insights into snoRNA-guided 2-O-ribose methylation.

bioRxiv · Jan 19, 2016Bioinformatics

Ewing sarcoma breakpoint region 1 prevents transcription-associated genome instability

Nitish Mittal, Christophe Kunz, Foivos Gypas, Shivendra Kishore, Georges Martin, Friedel Wenzel, Erik van Nimwegen, Primo Schaer, Mihaela Zavolan

This study shows that EWSR1 prevents DNA double-strand breaks by binding to intronic regions in its own locus and maintaining genomic stability.

bioRxiv · Dec 15, 2015 · PreprintSystems Biology

A comprehensive analysis of 3′ end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogenous ribonucleoprotein C on cleavage and polyadenylation

Andreas J Gruber, Ralf Schmidt, Andreas R Gruber, Georges Martin, Souvik Ghosh, Manuel Belmadani, Walter Keller, Mihaela Zavolan

The paper analyzes 3′ end sequencing data to identify novel polyadenylation signals and demonstrates HNRNPC's repressive role in poly(A) site usage and 3′ end processing.

bioRxiv · Nov 26, 2015Genomics