The HOTAIRM1-miR-222 Axis Regulates Venetoclax Resistance and Defines a High-Risk Subset in Pediatric t(8;21) Acute Myeloid Leukemia
Christine Wilson, Priyanka Swaroop, Vikas Gaur, Diwakar Sharma, Tanuja Bhardwaj, Sachin Kumar, Anita Chopra, Sampa Ghose, Jayanth Kumar Palanichamy, Deepam Pushpam, Ranjit Kumar Sahoo, Sameer Bakhshi, Surender Kumar Sharawat
The paper identifies HOTAIRM1-miR-222 axis as a regulator of venetoclax resistance and a marker of high-risk t(8;21) AML in pediatric patients.
bioRxiv · Jul 12, 2025 · PreprintCancer Biology