Sachin Kumar

This study shows estrogen enhances Japanese Encephalitis Virus replication in neuronal cells via the ER-PGC-1 axis and identifies it as a potential target for sex-specific therapies.

This study shows PKM2 reduces JEV replication by interacting with NS1, highlighting a new role for PKM2 in viral neuropathogenesis.

The paper identifies HOTAIRM1-miR-222 axis as a regulator of venetoclax resistance and a marker of high-risk t(8;21) AML in pediatric patients.

This study compares the immunomodulatory effects of hypoxia-preconditioned bone marrow and Wharton's jelly mesenchymal stem cells in acute graft-versus-host disease, finding WJ-MSCsHYP more effective due to enhanced mitochondrial transfer and metabolic reprogramming.

This study shows that hypoxia and apoptosis conditioning of WJ-MSCs enhances their immune regulatory capacity in aGVHD by promoting Treg differentiation and M2 macrophage polarization.

The paper analyzes SARS-CoV-2 genomes from Gujarat to identify variants associated with mortality and pathogenesis, finding specific mutations linked to increased disease severity.