Loss of mutually protective effects between osteoclasts and chondrocytes in damaged joints drives osteoclast-mediated cartilage degradation via matrix metalloproteinases
Q. C. Larrouture, A. P. Cribbs, S. J. Snelling, H. J. Knowles
This study shows that osteoclasts degrade cartilage via MMPs, and their protective interaction with chondrocytes is lost in damaged joints.
bioRxiv · Jan 3, 2021 · PreprintCell Biology