Cardiac contraction and relaxation are regulated by beta 1 adrenergic receptor generated cAMP pools at distinct membrane locations
T.-Y. Lin, Q. N. Mai, H. Zhang, E. Wilson, H.-C. Chien, S. W. Yee, K. M. Giacomini, J. E. Olgin, R. Irannejad
The paper shows that beta 1 adrenergic receptor-generated cAMP pools at distinct membrane locations regulate cardiac contraction and relaxation through different PKA targets.
bioRxiv · Jul 13, 2022 · PreprintCell Biology