Author

Q. Vicens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:structural biology· 3 Approach:biophysical modeling· 2 Research Focus:cell type annotation· 2 Organism:plant (other)· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Assay:cryo-EM· 1

Frequent Co-Authors

J. S. Kieft· 6 shared A.-L. Steckelberg· 3 shared M. J. Szucs· 3 shared R. A. Jones· 2 shared B. M. Akiyama· 1 shared C. J. Langeberg· 1 shared D. A. Costantino· 1 shared E. Mondragon· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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6 shared papersMicrobiology

J. S. Kieft

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Tick-borne flavivirus exoribonuclease-resistant RNAs contain a 'double loop' structure

J. S. Kieft, C. J. Langeberg, M. J. Szucs, M. E. Sherlock, Q. Vicens

The paper identifies and characterizes a novel 'double loop' structure in tick-borne flavivirus xrRNAs, revealing a conserved mechanism of exoribonuclease resistance.

bioRxiv · Apr 14, 2024Microbiology

Cryo-EM reveals an entangled kinetic trap in the folding pathway of a catalytic RNA

S. L. Bonilla, Q. Vicens, J. S. Kieft

The paper uses cryo-EM to visualize a long-lived misfolded state in the folding pathway of a catalytic RNA, revealing its structural features and implications for RNA folding mechanisms.

bioRxiv · Apr 5, 2022 · PreprintBiochemistry

A new subclass of exoribonuclease resistant RNA found in multiple Flaviviridae genera

M. J. Szucs, P. J. Nichols, R. A. Jones, Q. Vicens, J. S. Kieft

The paper identifies a new subclass of exoribonuclease resistant RNA (xrRNA) in multiple Flaviviridae genera, expanding the known distribution and structural diversity of xrRNAs.

bioRxiv · Jun 26, 2020Microbiology

Different tertiary interactions create the same important 3-D features in a divergent flavivirus xrRNA

R. A. Jones, A.-L. Steckelberg, M. J. Szucs, B. M. Akiyama, Q. Vicens, J. S. Kieft

The paper identifies an xrRNA in Tamana Bat Virus and shows it achieves a conserved 3D structure through novel tertiary interactions, highlighting sequence and structural diversity in flaviviruses.

bioRxiv · Jun 25, 2020Biochemistry

The crystal structure of a Polerovirus exoribonuclease-resistant RNA shows how diverse sequences are integrated into a conserved fold

A.-L. Steckelberg, Q. Vicens, D. A. Costantino, J. C. Nix, J. S. Kieft

The paper presents the crystal structure of a polerovirus xrRNA, revealing sequence diversity within a conserved fold and explaining conservation patterns and new interactions.

bioRxiv · Apr 30, 2020Biochemistry

Pervasiveness of exoribonuclease-resistant RNAs in plant viruses suggests new roles for these conserved RNA structures

A.-L. Steckelberg, Q. Vicens, J. S. Kieft

The paper identifies xrRNAs in diverse plant viruses, showing their presence in intergenic regions and association with coding subgenomic RNAs, suggesting broader roles beyond 3'UTR processing.

bioRxiv · Oct 2, 2018 · PreprintMicrobiology

Structure-activity relationship of flavin analogs that target the FMN riboswitch

Q. Vicens, E. Mondragon, F. E. Reyes, P. Coish, P. Aristoff, J. Bermann, H. Kaur, K. W. Wells, P. Wickens, J. Wilson, R. C. Gadwood, H. J. Schostarez, R. K. Suto, K. F. Blount, R. T. Batey

The paper describes the structure-based design of flavin analogs targeting the FMN riboswitch, identifying 5FDQD as an effective antibacterial compound.

bioRxiv · Aug 9, 2018Biochemistry