Author

R. T. Batey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:E. coli· 1

Frequent Co-Authors

A. E. Palmer· 2 shared A. J. Wierzba· 1 shared D. Gryko· 1 shared D. S. Wuttke· 1 shared E. BRASELMANN· 1 shared E. Mondragon· 1 shared F. E. Reyes· 1 shared H. J. Schostarez· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBiochemistry

A. E. Palmer

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Author profile →

6 papers

Recent·Most cited

The RNA-binding domain of hnRNP U extends beyond the RGG/RG motifs

O. A. Kletzein, D. S. Wuttke, R. T. Batey

This study identifies and characterizes the extended RNA-binding domain of hnRNP U, revealing two RGG/RG elements that work redundantly to enhance RNA binding.

bioRxiv · Sep 20, 2023Biochemistry

Context-dependence of T-loop mediated long-range RNA tertiary interactions

L. Hansen, O. A. Kletzien, M. Urquijo, L. T. Schwanz, R. T. Batey

The paper uses a genetic screen and bioinformatics to study context-dependent T-loop receptor interactions in riboswitches, finding restricted functional sequence space and distinct nucleobase-mediated interactions.

bioRxiv · Dec 26, 2022Biochemistry

Targeting riboswitches with beta-axial substituted cobalamins

S. R. Lennon, A. J. Wierzba, S. H. Siwik, D. Gryko, A. E. Palmer, R. T. Batey

This study investigates interactions between eleven cobalamin derivatives and three cobalamin riboswitches, showing plasticity and selectivity in RNA-ligand binding with potential for antibiotic development.

bioRxiv · Dec 25, 2022 · PreprintBiochemistry

Detection and quantification of single mRNA dynamics with the Riboglow fluorescent RNA tag

E. BRASELMANN, T. J. Stasevich, K. Lyon, R. T. Batey, A. E. PALMER

The paper introduces Riboglow, a fluorescent RNA tag for detecting and tracking single mRNA molecules in live cells, and benchmarks it against the MS2 system.

bioRxiv · Jul 13, 2019 · PreprintCell Biology

Structure-activity relationship of flavin analogs that target the FMN riboswitch

Q. Vicens, E. Mondragon, F. E. Reyes, P. Coish, P. Aristoff, J. Bermann, H. Kaur, K. W. Wells, P. Wickens, J. Wilson, R. C. Gadwood, H. J. Schostarez, R. K. Suto, K. F. Blount, R. T. Batey

The paper describes the structure-based design of flavin analogs targeting the FMN riboswitch, identifying 5FDQD as an effective antibacterial compound.

bioRxiv · Aug 9, 2018Biochemistry

Requirements for efficient cotranscriptional regulatory switching in designed variants of the Bacillus subtilis pbuE adenine-responsive riboswitch

L. K. Drogalis, R. T. Batey

The paper identifies sequence and structural features in the Bacillus subtilis pbuE riboswitch that influence cotranscriptional regulatory switching in response to adenine.

bioRxiv · Jul 19, 2018Biochemistry