"Two-Birds-One-Stone" Oral Nanotherapeutic Designed to Target Intestinal Integrins and Regulate Redox Homeostasis for Ulcerative Colitis Treatment
L. Huang, W. Hu, L. Q. Huang, Q. X. Zhou, Z. Y. Song, H. Y. Tao, B. Xu, C. Y. Zhang, Y. Wang, X.-H. Xing
This paper develops an oral nanotherapeutic, OPNs@LMWH, that targets intestinal integrins and regulates redox homeostasis to treat ulcerative colitis, showing improved therapeutic efficacy and immune uptake.
bioRxiv · Jan 2, 2024 · PreprintBioengineering