Multi-protein Bridging Factor 1(Mbf1), Rps3 and Asc1 prevent stalled ribosomes from frameshifting
Jiyu Wang, Jie Zhou, Qidi Yang, Elizabeth J. Grayhack
The paper shows that Mbf1, Rps3, and Asc1 prevent frameshifting in stalled eukaryotic ribosomes, unlike bacteria, by maintaining the reading frame through distinct mechanisms.
eLife · Nov 22, 2018Peer-reviewedMolecular Biology