Frameshifting at collided ribosomes is modulated by elongation factor eEF3 and by Integrated Stress Response regulators Gcn1 and Gcn20
Lisa Houston, Evan M. Platten, Sara M. Connelly, Jiyu Wang, Elizabeth J. Grayhack
The paper identifies eEF3 as a promoter and Gcn1/Gcn20 as suppressors of frameshifting at collided ribosomes in yeast, showing their distinct roles in quality control mechanisms.
RNA · Dec 16, 2021Peer-reviewedMolecular Biology