Germ-cell specific eIF4E1B regulates maternal RNA translation to ensure zygotic genome activation
Guanghui Yang, Qiliang Xin, Iris Feng, Di Wu, Jurrien Dean
The paper shows that eIF4E1B regulates maternal mRNA translation to enable zygotic genome activation by protecting chromatin remodeling and reprogramming factor mRNAs from degradation.
bioRxiv · Jul 27, 2022Developmental Biology