SLECA: a single-cell atlas of systemic lupus erythematosus enabling rare cell discovery using graph transformer
Maoteng Duan, Yao Shi, Hao Tian, Qiuqin Wu, Xiaoying Wang, Bingqiang Liu
SLECA creates a single-cell atlas of SLE to identify rare cell types, finding expanded double-negative T cells linked to disease severity and showing potential for therapeutic reprogramming.
Computational and Structural Biotechnology Journal · Mar 1, 2026Peer-reviewedBioinformatics