Author

R. Alexander Wesselhoeft

Mass General BrighamPrimary ORCID profile (0000-0003-4617-8157 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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R. Alexander WesselhoeftiD1 paper · Brigham and Women's Hospital

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Molecular Biology· 1

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Adam SychlaiD· 1 shared Anoop KrishnaniD· 1 shared Grant YangiD· 1 shared Jacob RulisoniD· 1 shared Namita BisariaiD· 1 shared Pierre BongrandiD· 1 shared Silvi RouskiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Adam SychlaORCID

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1 paper

Recent·Most cited

An RNA Language Model trained on sequence alone reveals the structural logic of Internal Ribosome Entry Sites

Adam Sychla, Pierre Bongrand, Grant Yang, Anoop Krishnan, Jacob Rulison, R. Alexander Wesselhoeft, Namita Bisaria, Silvi Rouskin

Continued pretraining of an RNA language model on picornaviral 5′ UTRs alone predicts IRES base pairs with median precision 0.80 versus 0.47 for Infernal, and reveals a Type II subclass.

bioRxiv · Sep 24, 2026 · PreprintMolecular Biology✦ In-depth digest