Atypical peripheral actin band formation via overactivation of RhoA and Non-muscle myosin II in Mitofusin 2 deficient cells
Y. Wang, L. D. Troughton, F. Xu, A. Chatterjee, H. Zhao, L. P. Cifuentes, R. B. Wagner, J. Chen, S. Kuang, D. M. Suter, C. Yuan, D. Chan, F. Huang, P. W. Oakes, Q. Deng
This study shows that MFN2 deficiency leads to increased cytosolic Ca2+ and overactivation of RhoA and non-muscle myosin II, causing atypical peripheral actin band formation in mouse embryonic fibroblasts.
bioRxiv · Oct 3, 2022Cell Biology