Author

R. Beaurepere

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Carreira· 1 shared A. De Reynies· 1 shared A. Ehlen· 1 shared A. El Marjou· 1 shared A. Kamoun· 1 shared C. Beraud· 1 shared C. Krucker· 1 shared C. Martin· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Carreira

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2 papers

Recent·Most cited

Integrated molecular and pharmacological characterization of patient-derived xenografts from bladder and ureteral cancers identifies new potential therapies.

H. Lang, C. Beraud, L. Cabel, M. Lassalle, J. Fontugne, C. Krucker, F. Dufour, C. S. Groeneveld, V. Dixon, X. Meng, A. Kamoun, E. Chapeaublanc, A. De Reynies, X. Game, P. Rischmann, , T. Massfelder

The paper develops patient-derived xenografts (PDXs) for bladder and ureteral cancers, identifies molecular subtypes, and shows that combined FGFR/EGFR inhibition is more effective than single-agent therapy for FGFR3-mutant tumors.

Frontiers in Oncology · Aug 11, 2022Peer-reviewedCancer Biology

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

A. Ehlen, C. Martin, S. Miron, M. Julien, F. X. Theillet, V. Ropars, G. Sessa, R. Beaurepere, V. Boucherit, P. Duchambon, A. El Marjou, S. Zinn Justin, A. Carreira

This study shows that BRCA2 phosphorylation by PLK1 is essential for proper chromosome alignment during mitosis, distinct from its DNA repair role, and its disruption leads to aneuploidy.

bioRxiv · Oct 26, 2019Cell Biology