Author

V. Ropars

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

P. Legrand· 2 shared S. Miron· 2 shared A. Carreira· 1 shared A. Ehlen· 1 shared A. El Marjou· 1 shared A. N. Zelensky· 1 shared A. Thureau· 1 shared A. Uryga· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

P. Legrand

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Author profile →

3 papers

Recent·Most cited

Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe

F. Ouasti, M. Audin, K. Freon, J.-P. Quivy, M. Tachekort, E. Cesard, A. Thureau, V. Ropars, P. F. Varela, G. Moal, I. Soumana-Amadou, A. Uryga, P. Legrand, J. Andreani, R. Guerois, , F. Ochsenbein

This study identifies how disordered regions and folded modules in SpCAF-1 from S. pombe enable histone deposition by mediating interactions with histones and PCNA during DNA replication.

bioRxiv · Jun 2, 2023Biochemistry

BRCA2-HSF2BP Oligomeric Ring Disassembly by BRME1 Promotes Homologous Recombination

R. Ghouil, S. Miron, K. Sato, D. Ristic, S. E. van Rossum-Fikkert, P. Legrand, M. Ouldali, J.-M. Winter, V. Ropars, G. David, A.-A. Arteni, C. Wyman, P. Knipscheer, R. Kanaar, A. N. Zelensky, S. Zinn-Justin

The paper shows that BRME1 disrupts the HSF2BP-BRCA2 ring complex, preventing BRCA2 degradation and promoting homologous recombination in meiosis.

bioRxiv · Apr 27, 2023Biochemistry

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

A. Ehlen, C. Martin, S. Miron, M. Julien, F. X. Theillet, V. Ropars, G. Sessa, R. Beaurepere, V. Boucherit, P. Duchambon, A. El Marjou, S. Zinn Justin, A. Carreira

This study shows that BRCA2 phosphorylation by PLK1 is essential for proper chromosome alignment during mitosis, distinct from its DNA repair role, and its disruption leads to aneuploidy.

bioRxiv · Oct 26, 2019Cell Biology