Author

R. Bornstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. Snell· 2 shared J. Stokes· 2 shared K. Y. Park· 2 shared M. M. Sedensky· 2 shared P. G. Morgan· 2 shared S. C. Johnson· 2 shared A. Freed· 1 shared A. Pan· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPathology

J. Snell

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Leukocyte proliferation mediates disease pathogenesis in the Ndufs4(KO) mouse model of Leigh syndrome

J. Stokes, R. Bornstein, K. James, K. Y. Park, K. Spencer, K. Vo, J. Snell, B. M. Johnson, P. G. Morgan, M. M. Sedensky, P. G. Morgan, N. A. Baertsch, S. C. Johnson

The paper shows that leukocyte proliferation drives Leigh syndrome pathology in Ndufs4(KO) mice, and leukocyte depletion prevents CNS lesions and extends survival.

bioRxiv · Nov 11, 2021 · PreprintPathology

Mechanisms underlying neonate specific metabolic effects of volatile anesthetics

J. Stokes, A. Freed, A. Pan, G. X. Sun, R. Bornstein, J. Snell, K. Y. Park, P. G. Morgan, M. M. Sedensky, S. C. Johnson

This study identifies a neonate-specific metabolic effect of volatile anesthetics, showing they deplete beta-hydroxybutarate at sub-anesthetic concentrations, mediated by citrate and malonyl-CoA changes, which adults are less sensitive to.

bioRxiv · Dec 8, 2020Physiology