Cell BiologybioRxivPreprint
Evolution of cullin E3 ubiquitin ligases and function in trypanosomes
R. C. del Pino, M. Zoltner, K. Yamada…·M. Field
The paper reconstructs the evolution of cullin-RING E3 ubiquitin ligases across eukaryotes and experimentally characterizes two cullin complexes in trypanosomatids, revealing lineage-specific diversity and novel substrate specificity.
DOI 10.1101/2023.07.24.550360