Human DNA-PK activates a STING-independent DNA sensing pathway
K. Burleigh, J. Maltbaek, S. Cambier, R. Green, M. Gale, R. C. James, D. B. Stetson
The paper identifies a STING-independent DNA sensing pathway in human cells, mediated by DNA-PK, and shows its role in antiviral responses and distinct activation from DNA damage.
bioRxiv · Mar 23, 2019Immunology