A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell therapy applications
D. Palianina, R. B. Di Roberto, R. C. Rueda, F. Schlatter, S. T. Reddy, N. Khanna
The paper introduces a method for CRISPR-targeted genome integration of a barcoded gene into antigen-specific T cells to enhance traceability and monitoring in adoptive cell therapy.
bioRxiv · Oct 31, 2022 · PreprintImmunology