Author

R. B. Di Roberto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Research Focus:clustering· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Assay:CUT&Tag· 1

Frequent Co-Authors

S. T. Reddy· 4 shared R. Vazquez-Lombardi· 3 shared A. Yermanos· 2 shared B. Wagner· 2 shared C. R. Weber· 2 shared D. M. Mason· 2 shared E. Kapetanovic· 2 shared F. Bieberich· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

S. T. Reddy

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Author profile →

4 papers

Recent·Most cited

A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell therapy applications

D. Palianina, R. B. Di Roberto, R. C. Rueda, F. Schlatter, S. T. Reddy, N. Khanna

The paper introduces a method for CRISPR-targeted genome integration of a barcoded gene into antigen-specific T cells to enhance traceability and monitoring in adoptive cell therapy.

bioRxiv · Oct 31, 2022 · PreprintImmunology

A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients

F. Bieberich, R. Vazquez-Lombardi, A. Yermanos, R. A. Ehling, D. M. Mason, B. Wagner, E. Kapetanovic, R. B. Di Roberto, C. R. Weber, M. Savic, F. Rudolf, S. T. Reddy

This study uses single-cell sequencing to analyze immune repertoires and transcriptomes in convalescent COVID-19 patients, revealing age-related differences in T and B cell responses.

bioRxiv · Feb 12, 2021Immunology

Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2

R. A. Ehling, C. R. Weber, D. M. Mason, S. Friedensohn, B. Wagner, F. Bieberich, E. Kapetanovic, R. Vazquez-Lombardi, R. B. Di Roberto, K.-L. Hong, C. Wagner, D. J. Sheward, B. Murrell, A. Yermanos, A. Cuny, , S. T. Reddy

Single-cell sequencing and screening identify expanded plasma cell clones in COVID-19 patients producing SARS-CoV-2-specific neutralizing antibodies.

bioRxiv · Feb 12, 2021 · PreprintImmunology

A functional screening platform for engineering chimeric antigen receptors with reduced on-target, off-tumour activation

R. B. Di Roberto, R. C. Rueda, S. Frey, D. Egli, R. Vazquez-Lombardi, S. T. Reddy

This study develops a functional screening platform to engineer CARs with reduced on-target, off-tumour activation by selecting for variants that respond only to high antigen expression.

bioRxiv · Apr 30, 2020Immunology