Endocrine-exocrine signaling drives obesity-associated pancreatic ductal adenocarcinoma
K. M. Chung, J. Singh, L. Lawres, K. J. Dorans, C. Garcia, D. B. Burkhardt, R. Robbins, A. Bhutkar, R. Cardone, X. Zhao, A. Babic, S. A. Vayrynen, A. Dias Costa, J. A. Nowak, D. T. Chang, , M. D. Muzumdar
This study shows obesity accelerates pancreatic cancer by altering the tumor microenvironment, with reversible effects through weight loss.
bioRxiv · Sep 26, 2019Cancer Biology