The desmosomal cadherin Desmoglein-3 regulates YAP and phospho-YAP in keratinocyte responses to mechanical forces
J. Uttagomol, U. S. Ahmad, A. Rehman, Y. Huang, A. C. Laly, A. Kang, J. Soetaert, R. Chance, M.-T. Teh, J. T. Connelly, H. Wan
This study shows that Dsg3 regulates YAP and phospho-YAP in keratinocyte mechanotransduction, affecting their response to mechanical forces and nuclear localization.
bioRxiv · Nov 1, 2019Cell Biology