A. Rehman

The host GTPase Dynamin 2 modulates apical junction structure to control cell-to-cell spread of Listeria monocytogenes

This study shows that Dynamin 2 and Tuba modulate apical junction structure to control cell-to-cell spread of Listeria monocytogenes by regulating cortical tension.

Intestinal epithelial Atg16l1 influences pregnancy-induced fecal microbiota shifts in mice

This study examines how Atg16l1 deletion in intestinal epithelial cells affects fecal microbiota shifts during pregnancy in mice, identifying altered microbial composition and functional potential.

Peripheral sgp130-mediated trans-signaling blockade induces obesity and insulin resistance in mice via PPARα suppression

This study shows that blocking peripheral sgp130-mediated trans-signaling in mice causes obesity and insulin resistance by suppressing PPARα.

Designing of a next generation multiepitope based vaccine (MEV) against SARS-COV-2: Immunoinformatics and in silico approaches

This paper designs a multiepitope vaccine against SARS-COV-2 using immunoinformatics and in silico methods, showing it is non-allergenic, antigenic, and binds strongly to TLR3 and TLR8.

The desmosomal cadherin Desmoglein-3 regulates YAP and phospho-YAP in keratinocyte responses to mechanical forces

This study shows that Dsg3 regulates YAP and phospho-YAP in keratinocyte mechanotransduction, affecting their response to mechanical forces and nuclear localization.

A large-scale comparison shows that genetic changes causing antibiotic resistance in experimentally evolved Pseudomonas aeruginosa predict those in naturally evolved bacteria

This paper experimentally evolves Pseudomonas aeruginosa to antibiotic resistance and identifies mutations that correlate with clinical isolates, showing their predictive value for resistance mechanisms.

Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms