RAS isoform specific activities are disrupted by disease associated mutations during cell differentiation
R. Chippalkatti, B. Parisi, F. Kouzi, C. Laurini, N. Ben Fredj, D. K. Abankwa
This study investigates how RAS isoform mutations affect cell differentiation using C2C12 myoblasts, finding distinct roles for K-Ras, N-Ras, and H-Ras and differential effects of pathway drugs.
bioRxiv · Oct 5, 2023Cell Biology