Cancer BiologybioRxiv
SREBP1 drives KRT80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer
L. Magnani, Y. Perone, A. Farrugia…·F. Calvo
This study identifies SREBP1-driven KRT80 upregulation as a mechanism promoting invasion in endocrine-resistant ERα breast cancer through cytoskeletal changes and increased tumor stiffness.
DOI 10.1038/s41467-019-09676-y