Author

F. Calvo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 6 Research Focus:cancer & tumor microenvironment· 5 Assay:bulk RNA-seq· 4 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Research Focus:differential expression· 2

Frequent Co-Authors

N. Ferrari· 2 shared A. Abaurrea· 1 shared A. Al-Malki· 1 shared A. Bryant· 1 shared A. Carracedo· 1 shared A. Chronopoulos· 1 shared A. D. Jenks· 1 shared A. del Rio Hernandez· 1 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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2 shared papersCancer Biology

N. Ferrari

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Dysregulated SASS6 expression promotes increased ciliogenesis and cell invasion phenotypes

E. Hargreaves, A. D. Jenks, A. S. Staszewski, A. Tsalikis, R. Bodoque Villar, M. Arias Garcia, Y. Abdi, A. Al-Malki, Y. Yuan, R. Natrajan, S. Haider, T. Iskratsch, W.-J. Wang, S. Godinho, N. J. Palaskas, , B. E. TANOS

This study shows that overexpression of SAS-6 promotes ciliogenesis and cell invasion through YAP/TAZ pathway activation, linked to poor cancer prognosis.

bioRxiv · Jan 29, 2024 · PreprintCell Biology

Stromal Oncostatin M axis promotes breast cancer progression

A. M. Araujo, A. Abaurrea, P. Azcoaga, J. I. Lopez-Velazco, R. Rezola, I. Osorio-Querejeta, F. Valdes-Mora, J. M. Flores, L. Jenkins, P. Fernandez-Nogueira, N. Ferrari, N. Martin-Martin, A. Tzankov, S. Eppenberger-Castori, I. Alvarez-Lopez, , C. H. Lawrie

This study identifies the stromal OSM:OSMR axis as a key driver of breast cancer progression by reprogramming the tumor microenvironment.

bioRxiv · Oct 30, 2020Cancer Biology

A mouse SWATH-MS reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts

L. Krasny, P. Bland, J. Burns, N. C. Lima, P. T. Harrison, L. Pacini, M. L. Elms, J. Ning, V. G. Martinez, Y.-R. Yu, S. E. Acton, P.-C. Ho, F. Calvo, A. Swain, B. A. Howard, , P. H. Huang

The paper develops a mouse SWATH-MS spectral library and a deconvolution method to analyze proteomic changes in human tumor xenografts, revealing host-tumor interactions.

bioRxiv · Feb 3, 2020Biochemistry

Cdc42EP5/BORG3 modulates SEPT9 to promote actomyosin function and melanoma invasion and metastasis

A. J. Farrugia, J. Rodriguez, J. L. Orgaz, M. Lucas, V. Sanz-Moreno, F. Calvo

This study shows Cdc42EP5 regulates melanoma invasion and metastasis by modulating SEPT9 to enhance actomyosin contractility and F-actin crosslinking.

bioRxiv · Dec 2, 2019Cancer Biology

Genomic and transcriptomic determinants of therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer

A. Woolston, K. Khan, G. Spain, L. J. Barber, B. Griffiths, R. Gonzalez Exposito, Y. Patil, S. Mansukhani, M. N. Davies, A. Furness, F. Sclafani, C. Peckitt, K. Kouvelakis, R. Ranftl, R. Begum, , M. Gerlinger

The paper analyzes genomic and transcriptomic data from CRC patients treated with cetuximab to identify resistance mechanisms and immune landscape changes during anti-EGFR therapy.

bioRxiv · Oct 19, 2018Cancer Biology

The dynamics of ERK signaling in melanoma, and the response to BRAF or MEK inhibition, are cell cycle dependent.

C. M. Simpson, N. Ferrari, F. Calvo, C. Bakal

This study shows ERK signaling in melanoma is cell cycle dependent, with distinct responses to BRAF or MEK inhibition before and after passing the restriction point.

bioRxiv · Aug 13, 2018 · PreprintCancer Biology

SREBP1 drives KRT80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer

L. Magnani, Y. Perone, A. Farrugia, A. Meira, B. Gyorffy, C. Ion, A. Uggetti, D. Patten, A. Chronopoulos, M. Faronato, S. Shousha, J. Steel, C. Davies, N. Patel, A. del Rio Hernandez, , F. Calvo

This study identifies SREBP1-driven KRT80 upregulation as a mechanism promoting invasion in endocrine-resistant ERα breast cancer through cytoskeletal changes and increased tumor stiffness.

bioRxiv · Jul 30, 2018Cancer Biology