Author

R. D. Socha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

N. Tokuriki· 2 shared A. N. Erdogan· 1 shared A. W. R. Serohijos· 1 shared B. E. Life· 1 shared D. Kehila· 1 shared J. Z. Chen· 1 shared L. Kiritchkov· 1 shared P. Dasmeh· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersEvolutionary Biology

N. Tokuriki

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2 papers

Recent·Most cited

Neutral Drift and Threshold Selection Promote Phenotypic Variation

A. N. Erdogan, P. Dasmeh, R. D. Socha, J. Z. Chen, B. E. Life, R. Jun, L. Kiritchkov, D. Kehila, A. W. R. Serohijos, N. Tokuriki

The paper shows neutral drift and threshold selection generate phenotypic variation in antibiotic resistance genes without adaptation.

bioRxiv · Apr 5, 2023Evolutionary Biology

The molecular mechanisms underlying hidden phenotypic variation among metallo-β-lactamases

N. Tokuriki, R. D. Socha

This paper investigates hidden phenotypic variation in metallo-β-lactamase (MBL) orthologs across different hosts, finding that resistance levels depend on both catalytic efficiency and periplasmic enzyme abundance.

bioRxiv · Sep 20, 2018Biochemistry