Author

R. D. Unwin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Adamson· 1 shared A. L. Hunter· 1 shared A. S. I. Loudon· 1 shared A. W. Trafford· 1 shared C. E. Pelekanou· 1 shared C. E. R. Smith· 1 shared C. M. Pearman· 1 shared D. A. Bechtold· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPhysiology

A. Adamson

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2 papers

Recent·Most cited

Adipocyte REVERBα dictates adipose tissue expansion during obesity

A. L. Hunter, C. E. Pelekanou, N. J. Barron, R. C. Northeast, A. Adamson, P. Downton, T. Cornfield, P. S. Cunningham, L. Hodson, A. S. I. Loudon, R. D. Unwin, M. Iqbal, D. W. Ray, D. A. Bechtold

This study shows adipocyte REVERBα regulates metabolic processes in white adipose tissue during obesity, preventing inflammation and fibrosis without affecting daily lipogenesis rhythms.

bioRxiv · Sep 23, 2020Physiology

Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.

M. Lawless, J. L. Caldwell, E. J. Radcliffe, C. E. R. Smith, G. W. Madders, D. C. Huthchings, L. S. Woods, S. J. Church, R. D. Unwin, G. J. Kirkwood, L. K. Becker, C. M. Pearman, R. F. Taylor, D. A. Eisner, K. M. Dibb, A. W. Trafford

This study shows that tadalafil improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure using a sheep model.

bioRxiv · Apr 2, 2019Physiology