Author

R. Done

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

A. Copland· 1 shared D. A. Lecky· 1 shared D. Bending· 1 shared E. K. Jennings· 1 shared E. S. Jinks· 1 shared L. Pallan· 1 shared L. S. George· 1 shared L. Sheriff· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Copland

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1 paper

Recent·Most cited

Lag3 and PD-1 pathways regulate NFAT-dependent TCR signalling programmes during early CD4+ T cell activation

L. Sheriff, A. Copland, D. A. Lecky, R. Done, L. S. George, E. K. Jennings, S. Rouvray, T. A. Elliot, E. S. Jinks, L. Pallan, D. Bending

This study shows that PD-1 and Lag3 pathways additively regulate TCR signal duration and NFAT-dependent transcription during early CD4+ T cell activation, with co-blockade enhancing NFAT-dependent gene expression.

bioRxiv · Jun 6, 2024 · PreprintImmunology