The influenza A virus host shutoff factor PA-X is rapidly turned over in a strain-specific manner
R. E. Levene, S. D. Shrestha, M. M. Gaglia
This study shows that the influenza A virus PA-X protein is rapidly turned over, with strain-specific half-lives influenced by sequences in its C-terminal domain, and longer half-life correlates with higher host shutoff activity.
bioRxiv · Aug 27, 2020Microbiology