Author

S. D. Shrestha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Bradley· 1 shared A. C. Powers· 1 shared A. D. Attie· 1 shared A. Shen· 1 shared C. Dai· 1 shared C. Feliciano· 1 shared E. D. Dean· 1 shared E. Spears· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPhysiology

A. Bradley

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pancreatic islet α cell function and proliferation requires the arginine transporter SLC7A2

E. Spears, J. E. Stanley, M. Shou, C. Dai, A. Bradley, L. Yin, X. Li, K. Sellick, G. Poffenberger, K. C. Coate, S. D. Shrestha, R. Jenkins, K. Sloop, K. T. Wilson, A. D. Attie, , E. D. Dean

This study identifies SLC7A2 as essential for α cell proliferation and glucagon secretion, linking arginine transport to metabolic regulation and HbA1c variation.

bioRxiv · Aug 10, 2023Physiology

Development of a dual fluorescent reporter system in Clostridioides difficile reveals a division of labor between virulence and transmission gene expression

M. L. Donnelly, S. D. Shrestha, J. W. Ribis, P. Kuhn, C. Feliciano, A. Shen, M. Krasilnikov

This study develops a dual fluorescent reporter system to analyze toxin and sporulation gene expression in C. difficile, revealing a division of labor between virulence and transmission gene expression under specific growth conditions.

bioRxiv · Mar 3, 2022Microbiology

The influenza A virus host shutoff factor PA-X is rapidly turned over in a strain-specific manner

R. E. Levene, S. D. Shrestha, M. M. Gaglia

This study shows that the influenza A virus PA-X protein is rapidly turned over, with strain-specific half-lives influenced by sequences in its C-terminal domain, and longer half-life correlates with higher host shutoff activity.

bioRxiv · Aug 27, 2020Microbiology