Shift of the insoluble content of the proteome in aging mouse brain
C. M. Molzahn, E. R. Kuechler, I. Zemlyankina, L. Nieves, T. Ali, G. Cole, J. Wang, R. F. Albu, M. Zhu, N. Cashman, S. Gilch, A. Karsan, P. F. Lange, J. Gsponer, T. Mayor
This study identifies age-related changes in the insoluble proteome of mouse brains, showing a shift in protein characteristics associated with proteostasis decline.
bioRxiv · Dec 13, 2022Cell Biology