Barcoded SARS-CoV-2 viruses define the impact of time and route of transmission on the transmission bottleneck in a Syrian hamster model.
R. F. Trende, Tamarand L. Darling, Tianyu Gan, David Wang, Adrianus C. M. Boon
This study uses barcoded SARS-CoV-2 viruses in Syrian hamsters to show that transmission bottleneck varies by exposure duration and route, with direct contact having the largest bottleneck.
Science Advances · Jan 15, 2025Peer-reviewedMicrobiology