Tamarand L. Darling

This study characterizes the antigenic properties of SARS-CoV-2 variants BA.3.2.1 and BA.3.2.2 in three animal models and finds they are antigenically divergent from existing variants with lower homologous serum titers.

Booster SARS-CoV-2 mRNA vaccine recruits and broadens GC B cell responses targeting a highly conserved site on receptor binding domain of spike glycoprotein.

This study uses barcoded SARS-CoV-2 viruses in Syrian hamsters to show that transmission bottleneck varies by exposure duration and route, with direct contact having the largest bottleneck.

6-Thioguanine inhibits SARS-CoV-2 PLpro protease activity and replication in cell cultures at submicromolar concentrations.