Quantitative phosphoproteomics reveals regulatory state dependent efficacy of chemical Cdk1 inhibition and distinct Cdk5 complexes as novel Wee1 substrates
A. V. Grassetti, R. Hards, S. A. Gerber
This study uses phosphoproteomics to show Wee1-dependent phosphorylation of Cdk1-cyclin B enhances RO3306 inhibition and identifies Cdk5 complexes as new Wee1 substrates.
bioRxiv · Sep 27, 2021 · PreprintCell Biology