Altered muscle niche contributes to myogenic deficit in the D2-mdx model of severe DMD
D. A. Mazala, R. Hindupur, Y. J. Moon, F. Shaikh, I. H. Gamu, D. Alladi, G. Panci, M. Weiss-Gayet, B. Chazaud, T. A. Partridge, J. S. Novak, J. K. Jaiswal
This study shows that altered muscle niche in D2-mdx mice leads to poor myogenesis and increased degeneration, but reversing this improves regeneration in adult mice.
bioRxiv · Mar 27, 2023 · PreprintPathology