Author

R. Holley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

A. Gorelik· 1 shared A. Palmigiano· 1 shared A. V. Pshezhetsky· 1 shared B. Amilhon· 1 shared B. Bigger· 1 shared B. Nagar· 1 shared C. W. Cairo· 1 shared D. Garozzo· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Gorelik

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Author profile →

1 paper

Recent·Most cited

Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins

T. Xu, R. Heon-Roberts, T. Moore, P. Dubot, X. Pan, T. Guo, C. W. Cairo, R. Holley, B. Bigger, T. Durcan, T. Levade, J. Ausseil, B. Amilhon, A. Gorelik, B. Nagar, , A. V. Pshezhetsky

This study shows that reduced NEU1 activity in neurological MPS leads to hypersialylation of brain glycoproteins, contributing to CNS pathology through disrupted synaptogenesis and behavior.

bioRxiv · Apr 26, 2024 · PreprintBiochemistry