Author

C. W. Cairo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. V. Pshezhetsky· 2 shared T. Guo· 2 shared A. Ahmad· 1 shared A. Gorelik· 1 shared A. Palmigiano· 1 shared B. Amilhon· 1 shared B. Bigger· 1 shared B. Nagar· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

A. V. Pshezhetsky

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Author profile →

3 papers

Recent·Most cited

Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins

T. Xu, R. Heon-Roberts, T. Moore, P. Dubot, X. Pan, T. Guo, C. W. Cairo, R. Holley, B. Bigger, T. Durcan, T. Levade, J. Ausseil, B. Amilhon, A. Gorelik, B. Nagar, , A. V. Pshezhetsky

This study shows that reduced NEU1 activity in neurological MPS leads to hypersialylation of brain glycoproteins, contributing to CNS pathology through disrupted synaptogenesis and behavior.

bioRxiv · Apr 26, 2024 · PreprintBiochemistry

The Janus-like role of neuraminidase isoenzymes in inflammation

M. A. Howlader, E. P. Demina, S. Samarani, T. Guo, A. Ahmad, A. V. Pshezhetsky, C. W. Cairo

This study shows that neuraminidase isoenzymes (NEU1, NEU3, NEU4) have opposing roles in regulating leukocyte recruitment during inflammation using a murine model.

bioRxiv · Jul 14, 2021Immunology

NEU1 and NEU3 enzymes alter CD22 organization on B cells

H.-T. T. Tran, C. Li, R. Chakraberty, C. W. Cairo

This study shows that NEU1 and NEU3 enzymes affect CD22 clustering and lateral mobility on B cells, influencing Ca2+ levels and potentially B cell activation.

bioRxiv · Apr 29, 2021Immunology