Author

A. V. Pshezhetsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

C. W. Cairo· 2 shared R. Heon-Roberts· 2 shared T. Guo· 2 shared T. Xu· 2 shared X. Pan· 2 shared A. Ahmad· 1 shared A. Gorelik· 1 shared A. L. A. Nguyen· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

C. W. Cairo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Secondary deficiency of neuraminidase 1 contributes to CNS pathology in neurological mucopolysaccharidoses via hypersialylation of brain glycoproteins

T. Xu, R. Heon-Roberts, T. Moore, P. Dubot, X. Pan, T. Guo, C. W. Cairo, R. Holley, B. Bigger, T. Durcan, T. Levade, J. Ausseil, B. Amilhon, A. Gorelik, B. Nagar, , A. V. Pshezhetsky

This study shows that reduced NEU1 activity in neurological MPS leads to hypersialylation of brain glycoproteins, contributing to CNS pathology through disrupted synaptogenesis and behavior.

bioRxiv · Apr 26, 2024 · PreprintBiochemistry

Oral Glucosamine Ameliorates Aggravated Neurological Phenotype in Mucopolysaccharidosis III Type C Mouse Model Expressing Misfolded HGSNAT Variant

X. Pan, M. Taherzadeh, P. Bose, R. Heon-Roberts, A. L. A. Nguyen, T. Xu, C. Para, Y. Yamanaka, D. A. Priestman, F. M. Platt, S. Khan, N. Fnu, S. Tomatsu, C. R. Morales, A. V. Pshezhetsky

This study shows oral glucosamine improves neurological symptoms in a mouse model with misfolded HGSNAT due to a Pro304Leu mutation.

bioRxiv · Aug 26, 2021Animal Behavior & Cognition

The Janus-like role of neuraminidase isoenzymes in inflammation

M. A. Howlader, E. P. Demina, S. Samarani, T. Guo, A. Ahmad, A. V. Pshezhetsky, C. W. Cairo

This study shows that neuraminidase isoenzymes (NEU1, NEU3, NEU4) have opposing roles in regulating leukocyte recruitment during inflammation using a murine model.

bioRxiv · Jul 14, 2021Immunology