Cell BiologyACS Central SciencePeer-reviewed
O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern
E. Gonzalez-Rodriguez, M. Zol-Hanlon, G. Bineva-Todd…·B. Schumann
This paper shows that O-linked sialoglycans affect SARS-CoV-2 spike proteolysis by furin and TMPRSS2, and may drive mutations in variants of concern.
DOI 10.1021/acscentsci.2c01349