R. Iwanaga

Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models

Loss of prdm1a accelerates melanoma onset and progression

This study shows that loss of PRDM1 accelerates melanoma onset and progression in zebrafish, with reduced PRDM1 expression linked to poor patient survival in humans.