Expressing the pro-apoptotic Reaper protein via insertion into the structural open reading frame of Sindbis virus reduces the ability to infect Aedes aegypti mosquitoes
This study expresses the pro-apoptotic Reaper protein in Sindbis virus to reduce infection in Aedes aegypti mosquitoes, showing reduced midgut and disseminated infection but not viral titer.
bioRxiv · Jan 13, 2022Microbiology