Human Milk Oligosaccharide 2'-fucosyllactose inhibits ligand binding to C-type lectin DC-SIGN but not to Langerin
R. Mukherjee, V. J. Somovilla, F. Chiodo…·A. Kraneveld
This study shows that 2'-fucosyllactose (2-FL) inhibits DC-SIGN ligand binding but not Langerin, with molecular dynamics revealing structural differences in binding modes.