Author

R. Jacquat

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Biophysics· 1

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Approach:experimental assay· 1

Frequent Co-Authors

A. J. Dear· 1 shared C. K. Xu· 1 shared E. Andrzejewska· 1 shared G. Krainer· 1 shared G. Meisl· 1 shared M. C. Cruz· 1 shared M. Vendruscolo· 1 shared S. LinseiD· 1 shared

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2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. J. Dear

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1 paper

Recent·Most cited

α-Synuclein oligomers form by secondary nucleation

C. K. Xu, G. Meisl, E. Andrzejewska, G. Krainer, A. J. Dear, M. C. Cruz, S. Turi, R. Jacquat, W. E. Arter, M. Vendruscolo, S. Linse, T. P. Knowles

This study shows α-synuclein oligomers form via secondary nucleation on fibril surfaces, not from monomers, and this process is enhanced by agitation under physiological conditions.

bioRxiv · May 28, 2023Biophysics