Senescent response in inner annulus fibrosus cells in response to TNFα, H2O2, and TNFα-induced nucleus pulposus senescent secretome
A. Montgomery-Song, S. Ashraf, P. Santerre, R. Kandel
This study investigates factors inducing senescence in inner annulus fibrosus cells and finds that TNFα and H2O2 have distinct effects, with TNFα-induced NP senescent secretome promoting iAF senescence.
bioRxiv · Dec 21, 2022Cell Biology